Topical corticosteroid therapy may be useful for stubborn localised lesions.ĬUTANEOUS DRUG REACTIONS: Cutaneous drug reactions are adverse reactions following systemic and topical drug administration. This condition is treated with immunosuppressive dosages of prednisolone with or without azathioprine. The diagnosis is supported by cytology and should in all cases be confirmed by histopathology. There are usually not systemic signs, but lesions may be painful. Bacteria are usually not present on cytology of intact pustules, but may contaminate ruptured lesions. Cytological examination of the purulent material will reveal large numbers of neutrophils and/or eosinophils and acantholytic keratinocytes which are highly suggestive of pemphigus foliaceus. In severe cases there may be pustule formation, greenish/yellowish discoloration and significant epithelial loss of the foot pads. The foot pads are usually swollen and hyperkeratotic with scaling, crusting, hardening and fissuring. It is characterized by a scaling, crusting and pustular dermatitis that usually affects the face, ear pinnae and foot pads. PEMPHIGUS FOLIACEUS: Pemphigus foliaceus is the most common of the pemphigus complex. Skin or foot pad biopsies for histopathology are required in many cases to make a final diagnosis. necrolytic migratory erythema (NME), whether one or more pads are affected and whether there are signs of skin disease elsewhere on the body. It is also important to determine whether there are concurrent systemic signs, e.g. genodermatoses, parasites and infectious diseases in young dogs versus auto-immune and metabolic conditions in older dogs). ![]() When a patient is presented with a foot pad condition it is important to take a good history and do a full clinical examination. There are also a few conditions that affect the foot pads only. There are not many foot pad conditions and therefore when the footpads are affected, they can aid in the diagnosis of a particular condition. Tel: 012 813 pad conditions are usually part of generalised skin conditions or systemic conditions that also cause skin lesions and clinical signs elsewhere on or in a patient.The most important differential diagnoses are discussed in this article. Willow Park Small Animal Medicine Specialist Hospital,
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